Thus, lorazepam diluted in bacteriostatic water for injection and stored in glass vials is stable for less than 7 days at 22c and for 7 days at 4c. Before you instigate the preparation process whereas the powder must be effectively mixed with the bacteriostatic water you will. Sterile water for injection, usp, must pass a particulatematter test that sterile water for irrigation, usp, does not have. Bacteriostatic water for injection is sterile, nonpyrogenic water that contains 0. Methylparaben and propylparaben are the preservatives containedin bacteriostaticwater for injection. Where water for injection is required for preparing or. A sterile version is used for making solutions that will be given by injection. Bacteriostatic water starter pack is a sterile bacteriostatic water for injection preparation kit used to mix, dilute and sterilize vials prior to. It is sterile, hypotonic, nonpyrogenic, and contains no bacteriostatic or antimicrobial agents. Bacteriostatic water for injection with baenzyl lcohol or bacteriostatic sodium chloride for injection with benzyl alcohol.
Other information bacteriostatic water for injection, usp is used for. Bacteriostatic water bacteriostatic water for injection is sterile water containing 0. This study sought to compare the in vitro physical properties and in vivo characteristics of two commonly employed echocardiographic saline contrast agents in an attempt to assess superiority. It is intended to be used as a diluent in the preparation of parenteral products, most typically for multidose products that require repeated. To mix the water and hcg together, you will take 2ml of the bacteriostatic water into your syringe, and add it to the ampoule of hcg. Sterile water for injection usp is a clear, colorless, odorless liquid. At 3 months the mean lorazepam concentration was 61% and 75% of the original concentration at 22c and 4c, respectively. Is bacteriostatic saline superior to normal saline as an. Sterile water for injection, usp is a hemolytic agent due to its hypotonicity. Bacteriostatic water for injection, usp by hospira. Sterile water for injection uspbacteriostatic water for. For patients sensitive to, serostim may be benzyl alcohol. Bacteriostatic water for injection bacteriostatic water for injection see usp monograph is sterile water for injection to which has been added one or more suitable antimicrobial preservatives. Bacteriostatic water for injections 2 qualitative and quantitative composition excipients with known effect.
Since we only do single use dosages for patients, we dont have bacteriostatic. Draw the fluid into the injection syringe by placing the needle into the bottom corner of the vial for full extraction. Bacteriostatic water is sterile water that contains a bacteriostat, a chemical that prevents the growth of bacteria in the vial. Sterile water for injection, usp and bacteriostatic water for injection, usp must be made approximately isotonic prior to use. Hcg will last about 2 weeks refridgerated in sterile water and about 5 weeks in. Dont forget to follow us on facebook for all the newest hcg diet updates and specials. However, the pharmacy instructions on the box direct me to add 10,000 ml. When creating bacteriostatic water, i go with the standard 0. Hemolysis may occur following infusion of sterile water for injection, usp.
This water is specially balanced to safeguard against infection whilst ensuring that the body is able to access the attached product effectively. Cefazolin sodium contd 1 cefazolin sodium contd 1 issued 1297 stability of cefazolin sodium reconstituted for im use. In the workplace, this material should be considered potentially irritating to the eyes and respiratory tract. Water for injection is water of extra high quality without significant contamination. Aug 01, 2019 bacteriostatic water for injection, usp is a sterile, nonpyrogenic preparation of water for injection containing 0. Not determined relevant identified uses of the substance or mixture and uses advised against intended use. Mixing instructions for hcg injections hcg diet info.
Bacteriostatic water for injection, usp is a sterile, nonpyrogenic, sterile water that contains 0. For 30 ml of bacteriostatic water you need 27 units of benzyl alcohol 0. Hospira, the worlds leading manufacturer and supplier of. Titan xl diluent sterile water for injection, preservative free intravenous iv solution flexible bag 3,000 ml. Disconnect the injection syringe from the vial and attach an. She instructed me to add 5,000 ml of the bacteriostatic water to reconstitute my hcg.
Sterile water for injection, usp, must pass a particulatematter test that sterile water for irrigation, usp, does not have to pass. How to abbreviate bacteriostatic water for injection. Hospira bacteriostatic water for injection usp is a chemically designed nonpyrogenic, sterile water used only to dissolve or dilute drugs prior to injection. I wouldnt increasedecrease it without being more knowledgeable about what youre doing than i am in regards to solubility in benzyl alcohol i wish i could find such numbers and post it here. List of marketing authorisations ma containing bacteriostatic water for injection registered and approved in europe on. Before such use other substances generally must be added to make the solution more or less isotonic. Bacteriostatic water for injection marketing authorisations. Bacteriostatic water for injection, usp is a sterile, nonpyrogenic preparation of water for injection containing 0. Disconnect the injection syringe from the vial and attach an appropriate needle for injection.
Summary of product characteristics 1 name of the medicinal product bacteriostatic water for injections 2 qualitative and quantitative composition excipients with known effect. Intravenous administration of sterile water for injection or bacteriostatic water for injection without a solute may result in hemolysis. This water is specially balanced to safeguard against infection whilst ensuring that the body is able to access the attached product. The small volume of fluid provided by sterile water for injection, usp or bacteriostatic water for injection, usp when used only as a pharmaceutic aid for diluting or dissolving drugs for parenteral injection, is unlikely to exert a significant effect on fluid balance except possibly in newborns or very small infants. Jul 15, 2014 objective data on the performance characteristics and physical properties of commercially available saline formulations normal saline ns vs. Bacteriostatic water is a different story though, it contains 0. Reconstituted etopophos solutions further diluted as directed can be stored under refrigeration 2 to 8c 36 to 46f or at room temperature 20 to 25c 68 to 77f for 24 hours. Side effects of bacteriostatic water bacteriostatic water. How to make your own bacteriostatic water for injection. Initial reconstitution of nplate with designated volumes of sterile water forinjection, uspresults in a concentration of 500mcgmlin all vial sizes. Bacteriostatic water for injection, usp chemical family.
The following preparation is designed solely for parenteral use only after addition of drugs that require dilution or must be dissolved in an aqueous vehicle prior to injection. Clearance sale hospira 20ml sterile water clearance sale. Brand name packaging size status date created date updated reports. Pharmaceutical product details of the supplier of the safety data sheet 2. Solumedrol methylprednisolone sodium succinate for. It is supplied in a multipledose container from which repeated withdrawals may be made to dilute or dissolve drugs for injection. First aid measures eye contact remove from source of exposure. Nov 28, 2019 the following preparation is designed solely for parenteral use only after addition of drugs that require dilution or must be dissolved in an aqueous vehicle prior to injection. Ive been through about 4 boxes of their needles and have gotten 2 vials of bacteriostatic water, shipping is usually 27 days, but since i live in florida and they are located in dunedin, fl it only. Bacteriostatic water a multiuse sterile water used for mixing or diluting solutions before injection. What is the difference between using sterile distilled water. We sell bacteriostatic water for injection to the australian public and also internationally. Bacteriostatic water for injection, unlike sterile water, is prepared with the benzyl alcohol to prevent the build up of bacteria and thus allows the vial to be used more than once, but should be discarded 28.
The sterile vial will have a rubber top, but the needle will pierce it easily so do not take the top off. Bacteriostatic sodium chloride for injection 10 ml. This delivery liquid comes in the form of bacteriostatic water. Sterile water for irrigation is not fda labeled for any use as an injection in patients. Bacteriostatic water for injection fda prescribing. Bacteriostatic normal saline vs bacteriostatic water for.
This preparation of sterile water and benzyl alcohol bnoh allows repeated withdrawals to be made from a single 30ml plastic vial. If irritation occurs or persists, get medical attention. May 07, 2020 using your syringe, take 3ml of bacteriostatic water and put it into the sterile vial. It is different from sterile water, which is filtered and purified but has no additives, and is usually only. Do not reconstitute or dilute with bacteriostatic water for. Bacteriostatic water for injection should be given to a pregnant woman only if clearly needed. For intramuscular, intravenous or subcutaneous injection. It is a diluent or solvent suitable for intravascular injection after first having been made approximately isotonic by the addition of suitable solute. It can be given by injection into a vein, muscle, or under the skin. Find patient medical information for water for injection, bacteriostatic injection on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Hemolysis may occur following infusion of sterile water for injection.
Rinse with plenty of water if skin irritation persists, call a physician. Ok, for all of you healthcare professionals, at the hospital we only use normal saline for injections, never water. The safety and effectiveness in the pediatric population are based on the similarity of the clinical conditions of. Msd online braun sterile water for injection ml msd. Bacteriostatic water for injection is prepared from water for injection that is sterilized and suitably packaged, containing one or more suitable antimicrobial agents. For patients sensitive to, serostim may be benzyl alcohol reconstituted with sterile water for injection, usp. If irritation persists or signs of toxicity occur, seek medical attention. Do not use bacteriostatic water for injection, usp for intravenous injection unless the osmolar concentration of additives results in an approximate isotonic admixture. Do not reconstitute or dilute with bacteriostatic water for injection, uspor dilute with bacteriostatic sodium chloride injection, usp.
The hcg bottle reads lyophilized chorionic gonadotrophin 10,000 unitshydroxocobalmin 5,000 mcg for injection. In addition to the specific tests, purified water that is packaged for commercial use elsewhere meets the additional requirements for packaging and storage and labeling as indicated under. Therefore, it is contraindicated for intravenous administration without additives. The most popular abbreviation for bacteriostatic water for injection is. Remove the filled syringe and insert needle squarely through the center of the stopper into the vial of powder. Bacteriostatic water is used to dilute or dissolve medications for patient injection.
Data is unavailable on the toxicity of such preservatives in newborns. Harm reduction how to make your own bacteriostatic water. This material is provided for educational purposes only. Important use only the accompanying diluent or bacteriostatic water for injection with benzyl alcohol when reconstituting solumedrol. Never give anything by mouth to an unconscious person. Titan xl container sterile water for injection usp is a clear, colorless, odorless liquid it is. Consult the manufacturers instructions for choice of vehicle, appropriate dilution or volume for dissolving the drugs to be injected, including the route and rate of injection. The packaged diluent bacteriostatic water for injection contains benzyl alcohol as a preservative. For 10 ml of bacteriostatic water, you will need 9 units of benzyl alcohol 0. Cefazolin sodium contd1 issued 1297 preparation and. Bacteriostatic water for injection, usp hospira inc. This preparation of sterile water and benzyl alcohol. Using your syringe, take 3ml of bacteriostatic water and put it into the sterile vial.
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